Kratom Buyer’s Guide

Everything You Need to Know Before You Buy Kratom

1. What is Kratom

Kratom, a tropical tree native to Southeast Asia, has gained significant attention worldwide for its potential benefits. Many kratom users report benefits such as pain relief, increased energy, mood enhancement, and lower anxiety. Some kratom enthusiasts have even used kratom to ease opiate withdrawal symptoms or to eliminate them completely.

As kratom grows in popularity, it’s easy to become overwhelmed with the large variety of products on the market. The challenge of choosing the right product amidst a sea of options can be daunting. This guide aims to equip you with the knowledge you need to make an informed decision before purchasing kratom. When you buy kratom, you want to buy the strain that will meet your needs. That’s why we have put together this guide. This kratom buyer’s guide contains everything you need to know before you buy kratom. We cover kratom strains, kratom effects, kratom dosage, kratom recipes, kratom consumption, the legality of kratom, and more!

2. Kratom Strains by Color 

Before you buy kratom, the first thing you need to learn about is kratom strains. Kratom comes in various strains, each with unique properties and effects. The three most common strains are:

Red Vein Kratom: Known for its relaxing and pain-relieving properties.

White Vein Kratom: Known for its energizing and stimulating effects.

Green Vein Kratom: Offers a balance between the effects of red and white strains, providing mild stimulation, relaxation, and a sense of well-being.

3. Kratom Strains by Region

Central to understanding which kratom will help you the most, is recognizing the distinctive effect of various color strains and how the growing region can boast unique alkaloid profiles that offer different effects. Let’s delve into the world of kratom strains, exploring their effects and potential applications.

1. Bali Kratom: Bali kratom is renowned for its potent analgesic properties, making it a popular choice for individuals seeking relief from chronic pain conditions. Its relaxing and sedating effects are also valued by those combating anxiety or seeking relaxation after a stressful day. Additionally, Bali kratom is often used during opiate withdrawal due to its ability to alleviate withdrawal symptoms and provide a sense of comfort.

2. Maeng Da Kratom: Maeng Da, known for its high alkaloid content, is prized for its energizing and stimulating effects. Users often turn to Maeng Da for increased focus, productivity, and mental clarity, making it a favorite among students, professionals, and those needing an extra boost to combat fatigue. It can also offer mild pain relief while maintaining alertness, making it a versatile option for daytime use.

3. Thai Kratom: Thai kratom is revered for its invigorating properties, often described as euphoric and mood-enhancing. It provides a boost in energy levels and mental alertness, making it suitable for individuals seeking motivation and productivity. Additionally, Thai kratom is utilized by some as a natural alternative to alleviate symptoms of depression and elevate mood.

4. Malay Kratom: Malay kratom is characterized by its balanced effects, offering a harmonious blend of energy and relaxation. It is frequently used to alleviate mild to moderate pain while promoting a sense of calmness and well-being. Malay kratom is also valued for its mood-lifting properties, making it beneficial for individuals struggling with stress, anxiety, or low mood.

5. Borneo Kratom: Borneo kratom is prized for its potent analgesic properties and relaxation-inducing effects. It is commonly used to manage chronic pain conditions, such as arthritis or fibromyalgia, providing relief without excessive sedation. Borneo kratom is also valued for its anxiolytic properties, making it beneficial for individuals seeking relief from anxiety or stress-related disorders.

4. Effects of Kratom

The effects of kratom vary significantly depending on dosage, with low doses typically producing stimulating and energizing effects, while higher doses tend to induce sedation and relaxation. Before you buy kratom and use it, it’s important to understand the effects of kratom.

At lower doses, kratom acts as a stimulant, enhancing focus, mood, and energy levels. Users may experience increased alertness, sociability, and motivation, making it a popular choice for boosting productivity or socializing. Moderate doses can elicit a balance of stimulating and sedating effects, providing relief from pain and anxiety while maintaining mental clarity.

However, at higher doses, kratom acts predominantly as a sedative, inducing feelings of calmness, euphoria, and relaxation. Users may experience deep relaxation, drowsiness, and even nodding off at very high doses.

It’s essential for users to carefully consider their dosage to achieve the desired effects while minimizing the risk of adverse reactions. Common effects include: 

Pain relief: Kratom may promote a pain-free lifestyle for people who suffer from chronic and acute pain.

Mood enhancement: Kratom may uplift mood and improve overall well-being.

Energy boost: Certain strains of kratom may provide increased energy and focus.

Relaxation: Kratom may induce a sense of calm and relaxation.

Improved focus: Some users report increased concentration and mental clarity.

5. Proper Dosage

Kratom Powder Dosage: Finding the right dosage is crucial to experience the desired effects and avoid adverse effects. Factors such as tolerance, body weight, and metabolism influence the optimal dosage. It is recommended to start with a low dose, typically 1/4 teaspoon, and gradually increase it as needed. A moderate dose ranges from 1/2 teaspoon to 1 teaspoon, while higher doses can be 1 teaspoon or more. However, it’s essential to follow dosage guidelines and avoid excessive consumption. When you buy kratom, take special notice of the product labeling to ensure you are taking the proper dose for the product you choose.

Kratom Capsules Dosage: Kratom capsules are a convenient and popular way to consume kratom. Because they are easily measurable and convenient to carry, kratom capsules are preferred for on-the-go kratom users. The following dosage recommendations are for kratom capsules containing kratom powder – NOT kratom extract. 

A low dose of kratom capsules (00 size capsules) is 1 to 2 capsules. A moderate dose is 2 to 4 capsules. A high dose is 5 or above.

Kratom Extract Dosage: Kratom extract dosage can vary depending on the strength of the extract. It is extremely important to read the dosage recommendations on the label or product description when buying kratom extract. Kratom USA’s 15X extract is sold in both powder and capsule form. Just one 15x capsule or just 1/8 teaspoon of 15x powder is considered a high dose. Kratom extract is typically used by seasoned kratom enthusiasts.

Kratom Tincture Dosage: Kratom tincture is highly popular because it’s so convenient to use and carry. Just slip the bottle into your pocket or purse, and you’re ready to face the day with a dose of highly concentrated premium kratom at your fingertips. Kratom USA offers 110MIT Premium Kratom Tincture that is highly effective in small doses.

A low dose of our tincture is 1/8 of a dropper. A moderate dose is 1/4 of a dropper. And a high dose is 1/2 or more of a dropper. 

6. Methods of Consumption

Kratom can be consumed in various ways, including:

Toss and Wash: This involves taking a desired amount of kratom powder and washing it down with a beverage. People who dislike the earthy taste of kratom may prefer this method.

Kratom Tea: Boiling kratom leaves to make a tea is a popular method. You can also add kratom powder or a dose of kratom tincture to hot water to make kratom tea. Adding flavored creamer or your favorite sweetening syrup is highly recommended. 

Capsules: Kratom is also available in pre-measured capsules for convenient consumption. Kratom USA uses standard 00-size capsules.

Kratom Tincture: This is a convenient form of liquid kratom that has been concentrated into a tincture. Many kratom users enjoy tinctures because of the convenient packaging. Kratom tincture is packaged in glass bottles with a dropper for simple, easy dosing.

Mixing with Food: Adding kratom powder to food, such as yogurt or smoothies, can mask the taste. Some users have added kratom to pudding or soft-serve ice cream for a quick, sweet treat. Due to the earthy taste of kratom, it may be helpful to follow our convenient recipe guide below for some easy kratom recipe ideas.

7. Kratom Recipes

Kratom Smoothie

Ingredients:

• Kratom powder (dose as per your requirement)
• 1 cup of milk (dairy or plant-based)
• 1 banana
• ½ cup of frozen berries
• 1 tablespoon of peanut butter
• Honey or agave syrup, to taste

Instructions:

1. Combine all ingredients in a blender, adding the kratom powder last.
2. Blend until smooth.
3. Taste and adjust sweetener as needed.
4. Serve immediately for the best flavor and effects.

Kratom Honey Balls

Ingredients:

• Kratom powder (dose as per your requirement)
• Honey
• Coconut flakes or cocoa powder for coating

Instructions:

1. In a bowl, mix your kratom dose with enough honey to form a thick paste. The amount of honey will vary depending on the kratom dose.
2. Once you have a consistent paste, take small amounts and roll them into balls.
3. Roll these balls in coconut flakes or cocoa powder to coat them.
4. Place the kratom honey balls in the refrigerator for an hour to set.
5. Enjoy one ball as your dose.

Kratom Tea and Oatmeal

Ingredients:

• Kratom powder (dose as per your requirement)
• 1 cup of water
• 1 cup of oats
• Honey or maple syrup, to taste
• Fresh fruits or nuts for topping

Instructions:

1. Prepare kratom tea by adding kratom powder to hot water.
2. Mix.
3. Prepare oatmeal with water or milk as you normally would.
4. Mix the kratom tea into the cooked oatmeal.
5. Sweeten with honey or maple syrup and top with your choice of fruits or nuts.

Kratom Yogurt Parfait

Ingredients:

• Kratom powder (dose as per your requirement)
• 1 cup of Greek yogurt
• ½ cup of granola
• Honey or maple syrup, to taste
• Fresh fruits for layering

Instructions:

1. In a bowl, mix the kratom powder with Greek yogurt until thoroughly combined.
2. In a serving glass or bowl, layer the kratom-infused yogurt with granola and fresh fruits.
3. Drizzle with honey or maple syrup to taste.
4. Repeat the layers until all ingredients are used.

Kratom Chocolate Chip Cookies

Ingredients:

• Kratom powder (dose as per your requirement, but spread across the batch)
• 1 cup of butter, softened
• 1 cup of white sugar
• 1 cup of packed brown sugar
• 2 eggs
• 2 teaspoons of vanilla extract
• 3 cups of all-purpose flour
• 1 teaspoon of baking soda
• 2 teaspoons of hot water
• ½ teaspoon of salt
• 2 cups of chocolate chips

Instructions:

1. Preheat your oven to 350°F (175°C).
2. Cream together the butter, white sugar, and brown sugar until smooth.
3. Beat in the eggs one at a time, then stir in the vanilla.
4. Dissolve baking soda in hot water and add to the batter along with salt.
5. Stir in flour, chocolate chips, and kratom powder.
6. Drop by large spoonfuls onto ungreased pans.
7. Bake for about 10 minutes or until edges are nicely browned.

Kratom Peanut Butter Sandwich

Ingredients:

• Kratom powder (dose as per your requirement)
• 2 slices of bread
• Peanut butter
• Honey or jelly (optional)

Instructions:

1. Spread peanut butter on one slice of bread.
2. Sprinkle your kratom dose evenly over the peanut butter.
3. Drizzle honey or jelly over the kratom if desired.
4. Top with the second slice of bread.
5. Cut in half and serve.

When experimenting with kratom in food, it’s important to start with a lower dose than you might take otherwise, especially if you are new to using kratom, to understand how your body reacts. Always ensure kratom is legal in your area and consult with a healthcare professional before starting any new supplement regimen.

Kratom Milkshake

Ingredients:

• Kratom powder (dose as per your requirement)
• 1 cup of milk (dairy or any plant-based milk like almond, coconut, or oat milk)
• 2 scoops of vanilla or chocolate ice cream
• 1 tablespoon of chocolate syrup (optional, for chocolate milkshake)
• ½ banana or a handful of strawberries (optional, for flavor)
• Whipped cream (optional, for topping)
• A few ice cubes (optional, for a colder shake)

Instructions:

1. Prepare Kratom: Start by mixing your kratom dose with a small amount of warm water to create a paste. This helps in evenly dispersing the kratom throughout the milkshake.
2. Blend Ingredients: In a blender, combine the milk, the kratom paste, ice cream, and any optional ingredients (chocolate syrup, banana, or strawberries). If you prefer a colder shake, add a few ice cubes.
3. Mix Until Smooth: Blend on high until all ingredients are thoroughly mixed and the milkshake is smooth.
4. Serve: Pour the milkshake into a glass and, if desired, top with whipped cream. Enjoy immediately.

Kratom Brownies

Ingredients:

• Kratom powder (dose divided by the number of brownies to ensure each has an appropriate amount)
• ¾ cup of unsalted butter
• 1½ cups of sugar
• ¾ cup of cocoa powder
• ½ teaspoon of salt
• 1 teaspoon of vanilla extract
• 3 large eggs
• 1 cup of all-purpose flour
• ½ cup of chocolate chips or nuts (optional)

Instructions:

1. Preheat Oven: Preheat your oven to 350°F (175°C). Grease a 9×9 inch baking pan or line it with parchment paper.
2. Melt Butter: In a medium saucepan, melt the butter over low heat. Remove from heat and stir in sugar and cocoa powder until well combined.
3. Add Kratom: Mix the kratom powder into the warm butter-sugar-cocoa mixture. This ensures the kratom is evenly distributed throughout the mixture.
4. Combine Wet Ingredients: Stir in salt, vanilla extract, and eggs, one at a time, mixing well after each addition.
5. Add Flour: Gently fold in the flour until just combined. Avoid overmixing. If desired, fold in chocolate chips or nuts.
6. Bake: Pour the batter into the prepared baking pan, spreading it out evenly. Bake for 20-25 minutes or until a toothpick inserted into the center comes out with a few moist crumbs.
7. Cool and Serve: Allow the brownies to cool in the pan before cutting into squares. The number of brownies will determine the dose of kratom per brownie, so cut accordingly.

When preparing recipes with kratom, it’s crucial to measure your doses carefully to ensure each serving contains an appropriate amount. Always start with a lower dose if you’re new to kratom or are unsure of its effects on your body. Also, keep in mind the legal status of kratom in your area and consult with a healthcare provider if you have any concerns about incorporating kratom into your diet.

Kratom Chocolate Bars Recipe

Ingredients:

• Kratom powder (total dose as per your requirement, divided by the number of bars you plan to make)
• 200g (about 7 oz) of dark chocolate or milk chocolate, according to preference
• 1 tablespoon of coconut oil (optional, for smoother chocolate)
• Nuts, dried fruits, or any other add-ins you prefer (optional)

Instructions:

1. Prepare Kratom Dose: Calculate the total amount of kratom you want to use based on the individual dose and how many bars you plan to make. This ensures each bar contains an appropriate amount of kratom.

2. Melt Chocolate: Break the chocolate into small pieces and melt it gently. You can use a double boiler or melt it in the microwave. If using a microwave, heat in short bursts of 20-30 seconds, stirring in between, to prevent burning. If you choose, mix in the coconut oil to make the chocolate mixture smoother.

3. Mix Kratom: Once the chocolate is melted and smooth, remove it from the heat and let it cool slightly. Then, thoroughly mix in your kratom powder to ensure it’s evenly distributed throughout the chocolate. If you have any additional ingredients like nuts or dried fruits, stir them in as well.

4. Pour into Molds: Carefully pour the kratom-infused chocolate mixture into chocolate bar molds. If you don’t have chocolate bar molds, you can use any small, shallow container or tray lined with parchment paper.

5. Cool: Place the molds or tray in the refrigerator or freezer to set. This process usually takes about 1-2 hours in the refrigerator or about 30 minutes in the freezer.

6. Unmold: Once the chocolate has completely set, gently remove the kratom chocolate bars from the molds. If you used a tray, you might need to cut the chocolate into bars or pieces.

Storage: Store the kratom chocolate bars in an airtight container in a cool, dry place, or in the refrigerator if your kitchen is warm. Remember to label them, especially if there are others in your household.

Note: When consuming kratom chocolate bars, start with a small portion to see how you react to the combination of kratom and chocolate, especially if you’re new to kratom. Adjust the amount of kratom based on your experience and tolerance level. Always ensure kratom is legal in your area and consult with a healthcare professional before starting any new supplement regimen.

Kratom No-Bake Chocolate Peanut Butter Balls Recipe

Ingredients:

• Kratom powder (dose as per your requirement, divided by the number of balls you plan to make)
• 1 cup of peanut butter (smooth or crunchy, based on preference)
• ¾ cup of semi-sweet chocolate chips
• 2 cups of rolled oats
• ½ cup of ground flaxseed (optional, for added nutrition)
• 1/3 cup of honey or maple syrup
• 1 teaspoon of vanilla extract
• A pinch of salt (if using unsalted peanut butter)
• Additional coatings (optional): cocoa powder, crushed nuts, or shredded coconut for rolling

Instructions:

1. Prepare Kratom Mixture: In a large bowl, start by mixing the kratom powder with the peanut butter to ensure the kratom is evenly distributed. This helps in masking the kratom taste effectively.

2. Melt Chocolate: In a microwave-safe bowl or using a double boiler, gently melt the chocolate chips until smooth. If using a microwave, heat in 20-30 second bursts, stirring in between to avoid burning the chocolate.

3. Combine Ingredients: Add the melted chocolate to the peanut butter and kratom mixture. Then, stir in the rolled oats, ground flaxseed (if using), honey or maple syrup, vanilla extract, and a pinch of salt. Mix well until all ingredients are thoroughly combined and the mixture is uniform.

4. Chill Mixture: If the mixture is too soft to handle, place it in the refrigerator for about 10-15 minutes to firm up slightly. This will make it easier to roll into balls.

5. Form Balls: Using a spoon or a cookie scoop, take small amounts of the mixture and roll them into balls. Depending on your preference, you can make them bite-sized or larger.

6. Coat Balls (Optional): Roll each ball in your choice of additional coatings, such as cocoa powder, crushed nuts, or shredded coconut, to add an extra layer of flavor and texture.

7. Refrigerate to Set: Place the formed balls on a baking sheet lined with parchment paper and refrigerate for at least 30 minutes to allow them to set and firm up.

8. Storage: Once set, transfer the kratom chocolate peanut butter balls to an airtight container and keep them refrigerated. Enjoy them as a convenient and tasty kratom-infused treat.

Note: It’s important to consider the total amount of kratom you’re using and divide it appropriately among the balls to ensure consistent dosing. Start with a small serving to gauge your tolerance, especially if you’re new to kratom. Always check the legal status of kratom in your area and consult with a healthcare professional before incorporating kratom into your diet.

8. Kratom DIY: Make Your Own Kratom Gummies

Making your own kratom gummies is a creative way to consume kratom, especially if you find the taste of kratom powder to be too strong or unpleasant. These gummies can be customized with your preferred flavors and dosages. If you want to try something fun after you buy kratom, use this simple recipe to make kratom gummies at home!

Creating your own kratom tincture can be a fun alternative to buying kratom tincture. Making kratom tincture is a process that involves extracting the active alkaloids from kratom powder or leaves and turning them into a liquid form. This method allows for easy dosage and a longer shelf life. Here’s a basic guide to making your own kratom tincture at home:

Ingredients and Materials:

• Kratom powder or leaves (quantity depending on how potent you want your tincture to be)
• High-proof alcohol (ethanol) like Everclear, which is preferable for extraction. The alcohol should be at least 40-50% alcohol by volume (80-100 proof), but higher is better.
• Citric acid or lemon juice to adjust the pH
• A glass jar with a tight-fitting lid
• Cheesecloth or a fine strainer
• Dark glass dropper bottles for storage
• pH test strips (optional)

Instructions:

Prepare Your Kratom: If using kratom leaves, grind them into a fine powder. The amount of kratom you use will determine the potency of your tincture. A common ratio is 4 ounces of kratom powder to 1 liter of alcohol, but you can adjust this depending on how strong you want the tincture to be.

 Mix with Alcohol: Place the kratom powder in the glass jar, and pour enough high-proof alcohol over it to cover the powder plus an extra inch or two above it. The exact amount of alcohol is not crucial as long as the kratom is fully submerged.

 Adjust pH: Add citric acid or lemon juice to the mixture until the pH is around 4. This acidic environment helps with the extraction of alkaloids. Use pH test strips to check the acidity level.

 Shake and Store: Seal the jar tightly and shake it vigorously to mix everything thoroughly. Store the jar in a cool, dark place. Shake the jar once or twice daily to agitate the mixture, which aids in the extraction process.

 Let It Sit: Allow the mixture to sit for at least a few weeks, up to a month or longer. The longer it sits, the more potent the tincture may become as more alkaloids are extracted.

 Strain the Mixture: After the desired steeping time, strain the liquid through a cheesecloth or fine strainer to remove all solid particles. You might need to do this several times to get a clear liquid.

 Reduce (Optional): If you want a more concentrated tincture, you can gently evaporate some of the alcohol. Pour the strained liquid into a shallow pan and let it sit in a well-ventilated area. Be very cautious with this step since alcohol fumes are flammable. Do not use direct heat.

 Bottle Your Tincture: Transfer the final tincture into dark glass dropper bottles for storage. Label the bottles with the date and potency if known.

 Storage: Store your kratom tincture in a cool, dark place. The alcohol preserves the alkaloids, so your tincture can last for many years without losing potency.

Notes:

• The potency of your tincture will depend on the ratio of kratom to alcohol and the length of time you allow the mixture to steep.
• Always start with a small dose to assess the strength and effects of your tincture, especially if it’s your first time making it.
• Ensure kratom is legal in your area, and consult with a healthcare provider before using kratom, especially if you have underlying health conditions or are taking medications.

Creating a kratom tincture at home allows for customization and can be a cost-effective way to use kratom. Enjoy your homemade tincture responsibly!

10. Potential Risks and Precautions

While kratom is generally considered safe, it’s important to be aware of potential risks and take precautions:

Dependency and Withdrawal: Prolonged and excessive use of kratom may lead to dependence and withdrawal symptoms.

Drug Interactions: Kratom may interact with certain medications, so it’s important to consult a healthcare professional if you’re taking any prescription drugs.

Quality Control: Ensure you purchase kratom from reputable vendors to avoid adulterated or contaminated products.

Individual Reactions: People react differently to kratom, so it’s important to start with a low dose and observe how your body responds.

11. Legality and Regulations

The legal status of kratom varies by country and region. Some countries have banned or strictly regulated its use, while others allow it for personal use or for research purposes. Before purchasing or using kratom, familiarize yourself with the laws in your area to avoid any legal issues.

Pharmacological Studies

Here is a list of the current legal status of kratom in each state in the U.S.

1. Alabama: Kratom is listed as a Schedule I controlled substance.
2. Arkansas: Kratom is banned.
3. California: Kratom is legal except in San Diego, where it is banned.
4. Colorado: Kratom is legal for those aged 18 and older.
5. Connecticut: Kratom is legal for those aged 21 and older.
6. Delaware: Kratom is legal for those aged 18 and older.
7. Florida: Kratom is legal for those aged 18 and older.
8. Georgia: Kratom is legal for those aged 18 and older.
9. Idaho: Kratom is legal.
10. Illinois: Kratom is legal for those aged 18 and older.
11. Indiana: Kratom is banned.
12. Iowa: Kratom is legal.
13. Kansas: Kratom is legal.
14. Kentucky: Kratom is legal.
15. Louisiana: Kratom is legal.
16. Maine: Kratom is legal for those aged 21 and older.
17. Maryland: Kratom is legal.
18. Massachusetts: Kratom is legal.
19. Michigan: Kratom is legal.
20. Minnesota: Kratom is legal.
21. Mississippi: Kratom is legal.
22. Missouri: Kratom is legal.
23. Montana: Kratom is legal.
24. Nebraska: Kratom is legal.
25. Nevada: Kratom is legal.
26. New Hampshire: Kratom is legal.
27. New Jersey: Kratom is legal.
28. New Mexico: Kratom is legal.
29. New York: Kratom is legal.
30. North Carolina: Kratom is legal.
31. North Dakota: Kratom is legal.
32. Ohio: Kratom is legal.
33. Oklahoma: Kratom is legal.
34. Oregon: Kratom is legal.
35. Pennsylvania: Kratom is legal.
36. Rhode Island: Kratom is legal.
37. South Carolina: Kratom is legal.
38. South Dakota: Kratom is legal.
39. Tennessee: Kratom is legal.
40. Texas: Kratom is legal.
41. Utah: Kratom is legal.
42. Vermont: Kratom is legal.
43. Virginia: Kratom is legal.
44. Washington: Kratom is legal.
45. West Virginia: Kratom is legal.
46. Wisconsin: Kratom is banned.
47. Wyoming: Kratom is legal.

Kratom Legal Status in Certain Municipalities:

1. San Diego, California: Kratom is banned.
2. Jerseyville, Illinois: Kratom is banned.
3. Sarasota County, Union County, and City of Denver, Colorado: Kratom is banned.

Remember, this guide provides general information about kratom, but it’s important to conduct further research, consult reputable sources, and, if needed, seek guidance from healthcare professionals before using kratom.

12. Kratom Studies

Kratom (Mitragyna Speciosa) has been the focus of various studies due to its pharmacologically active compounds, primarily mitragynine and 7-hydroxymitragynine. These studies range from its pharmacokinetics to its potential for both therapeutic use and abuse. Here’s an overview of the types of studies conducted on kratom:

Photo credit: https://www.hopkinsmedicine.org/news/newsroom/news-releases/2020/02/natural-herb-kratom-may-have-therapeutic-effects-and-relatively-low-potential-for-abuse-or-harm-according-to-a-user-survey

Pharmacological Studies

Researchers have investigated how kratom acts on various neurotransmitter systems. The primary active alkaloid, mitragynine, acts as a partial agonist at mu-opioid receptors, which can produce analgesia and euphoria. Studies suggest that its complex pharmacological profile may contribute to mitragynine’s interaction with other receptor systems, such as adrenergic, serotonergic, and dopaminergic pathways.

A recent study from Johns Hopkins found that kratom “may have therapeutic effects and relatively low potential for abuse or harm.”

Therapeutic Potential

Clinical research into kratom’s potential therapeutic effects is still in the early stages. There are anecdotal reports and preliminary studies suggesting potential benefits for pain management, opioid withdrawal relief, and mood enhancement. However, controlled clinical trials are necessary to verify these effects and to understand the appropriate dosages and treatment protocols.

Toxicology and Safety Profile

Toxicological studies have been conducted to assess the safety profile of kratom. Concerns have been raised regarding the potential for toxicity. The results have been mixed, with some studies indicating potential risks and others suggesting a relatively low risk when used responsibly.

Abuse and Addiction Potential

Studies have also examined kratom’s potential for abuse and addiction. Some users report dependence and withdrawal symptoms similar to those of opioids but significantly milder. Other users report little to no withdrawal symptoms. Research continues to investigate the potential for kratom therapy uses.

Regulatory Studies

Regulatory bodies, including the FDA and DEA in the United States, have been evaluating scientific studies to determine the appropriate legal status for kratom. While some advocate for its use as an alternative to traditional opioids, others are concerned about its potential for abuse and harm.

Ethnobotanical and Cultural Studies

Ethnobotanical research on kratom has documented its traditional uses in Southeast Asia for pain, fatigue, stomach ailments, and as a substitute for opium. Cultural studies have provided context for its traditional consumption and the shift towards its use in the West.

Recent Developments

Kratom is still a subject of debate within the scientific community and regulatory agencies. The FDA has not approved kratom for any medical use. At the same time, researchers and advocates argue for the need for more comprehensive studies to fully understand its potential.

Conclusion

The current body of research on kratom is growing, but more extensive and rigorous scientific studies are needed to determine its efficacy as a therapeutic agent. While some users advocate for its benefits based on personal experiences, healthcare professionals and researchers call for a measured approach due to the lack of standardization. As interest in kratom continues to increase, so does the importance of conducting thorough research to inform public policy and healthcare practices.

Watch the latest Congressional briefing on kratom science here.